Using behavioral and neuroimaging methods, we investigate the cognitive and neural mechanisms of memory and emotion and how they change across the lifespan.

The “illusory truth” effect refers to the phenomenon whereby repetition of a statement increases its likelihood of being judged true. Behavioral evidence suggests that illusory truth should be mediated by brain regions previously linked to fluency, such as the perirhinal cortex (PRC). To investigate this possibility, we scanned participants with fMRI while they rated the […]

A common approach in memory research is to isolate the function(s) of individual brain regions, such as the hippocampus, without addressing how those regions interact with the larger network. To investigate the properties of the hippocampus embedded within large-scale networks, we used functional magnetic resonance imaging and graph theory to characterize complex hippocampal interactions during […]

Nerve fibers of the corpus callosum, the big data cable linking both sides of the human brain, are the focus of our recent paper in the Journal of Neuroscience. Both structural and functional connectivity were mapped across the callosum as subjects were asked to perform word- and face-recognition tasks of increasing difficulty. Subjects demonstrated a “bilateral processing […]

“Holiday shopping can be mentally exhausting for anyone. But a new Duke University study finds that older adults seem to need extra brainpower to make shopping decisions — especially ones that rely on memory.” The work of Nichole Lighthall, a postdoctoral researcher in Roberto Cabeza’s lab, is featured in a Duke Today article.

A fundamental idea in memory research is that items are more likely to be remembered if encoded with a semantic, rather than perceptual, processing strategy. Interestingly, this effect has been shown to reverse for emotionally arousing materials, such that perceptual processing enhances memory for emotional information or events. The current fMRI study investigated the neural […]

The Society of Experimental Psychologists is the oldest and most prestigious honorary society in Psychology.

Restudying material is a common method for learning new information, but not necessarily an effective one. Research on the testing effect shows that practice involving retrieval from memory can facilitate later memory in contrast to passive restudy. Despite extensive behavioral work, the brain processes that make retrieval an effective learning strategy remain unclear. In the […]

The reliable neuroimaging finding that older adults often show greater activity (over-recruitment) than younger adults is typically attributed to compensation. Yet, the neural mechanisms of over-recruitment in older adults (OAs) are largely unknown. Rodent electrophysiology studies have shown that as number of afferent fibers within a circuit decreases with age, the fibers that remain show higher synaptic field potentials (less […]

   Although it is well established that the perirhinal cortex (PRC) makes an important contribution to recognition memory, the specific nature of this contribution remains uncertain. The finding that PRC activity is reduced for old compared to new items is typically attributed to the recovery of a long-term memory signal. However, because old items are […]

The present investigation tested the novel prediction that encoding-retrieval similarity can be observed and related to memory at the level of individual items. Multivariate representational similarity analysis was applied to functional magnetic resonance imaging (fMRI) data collected during encoding and retrieval of emotional and neutral scenes. Memory success tracked fluctuations in encoding-retrieval similarity across frontal and posterior cortices. Importantly, memory […]