Lab Manager Position in Cognitive Neuroscience Laboratory A lab manager position is available in the laboratory of Roberto Cabeza (www.cabezalab.org) at the Center for Cognitive Neuroscience of Duke University (www.mind.duke.edu). fMRI scanning (www.biac.duke.edu) and TMS (http://sites.google.com/site/duken3lab/) facilities are located within a few hundred yards. Research at the Cabeza Lab focuses on the neural mechanisms of [...]
The present investigation tested the novel prediction that encoding-retrieval similarity can be observed and related to memory at the level of individual items. Multivariate representational similarity analysis was applied to functional magnetic resonance imaging (fMRI) data collected during encoding and retrieval of emotional and neutral scenes. Memory success tracked fluctuations in encoding-retrieval similarity across frontal and posterior cortices. Importantly, memory [...]
Although ventral parietal cortex (VPC) activations can be found in a variety of cognitive domains, these activations have been typically attributed to cognitive operations specific to each domain. In this article, we propose a hypothesis that can account for VPC activations across all the cognitive domains reviewed. We first review VPC activations in the domains of perceptual and motor [...]
Studies of cognitive and neural aging have recently provided evidence of a shift from an early- to late-onset cognitive control strategy, linked with temporally extended activity in the prefrontal cortex (PFC). It has been uncertain, however, whether this age-related shift is unique to PFC and executive control tasks, or whether the functional location might vary [...]
Dew and Cabeza (2011) review behavioral and neuroimaging evidence showing that, under certain circumstances, there may be an important and influential relationship between conscious and nonconscious forms of memory. Here, we offer a model predicting that the brain regions associated with explicit or implicit memory are not differentiated based on consciousness, but rather vary along [...]
Emotion processing has been shown to vary with age: relative to young adults (YAs), older adults (OAs) exhibit increased frontal activations to emotional materials as well as cognitive biases toward positive versus negative stimuli. This latter effect is hypothesized to depend on OAs’ capacity for controlled elaboration. To test this hypothesis, YAs and OAs [...]
Whereas ventral mPFC (medial prefrontal cortex) has been associated with inferences about one’s own self, dorsal mPFC has been associated with inferences about others. We investigated this distinction using a novel camera technology that automatically takes hundreds of photographs when worn. We fMRI-scanned young participants while viewing movie clips depicting events from their own life [...]
Many studies in our lab focus on the fact that, as we age, our brains start to use two hemispheres when our younger selves used just one. This phenomenon, called contralateral recruitment, remains controversial because its neural correlates are still poorly understood. To investigate this phenomenon, we used a lateralized word-matching paradigm that emphasized either [...]
Major depressive disorder (MDD) is characterized by the presence of disturbances in emotional processing and its associated neural responses. A critical question in this domain is whether the neural correlates of these alterations are affected by therapeutic interventions. This study used fMRI to compare neural responses to emotionally positive, negative, and neutral pictures in patients [...]
Older adults recall less episodically rich autobiographical memories (AM), however, the neural basis of this effect is not clear. Using functionalMRI, we examined the neural correlates supporting memory retrieval while young and older adults searched for and elaborated upon AMs. Our results suggest that the age-related attenuation in the episodic richness of AMs is associated [...]