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A fundamental idea in memory research is that items are more likely to be remembered if encoded with a semantic, medical rather than perceptual, no rx processing strategy. Interestingly, this effect has been shown to reverse for emotionally arousing materials, such that perceptual processing enhances memory for emotional information or events. The current fMRI study […]

The reliable neuroimaging finding that older adults often show greater activity (over-recruitment) than younger adults is typically attributed to compensation. Yet, advice the neural mechanisms of over-recruitment in older adults (OAs) are largely unknown. Rodent electrophysiology studies have shown that as number of afferent fibers within a circuit decreases with age, search the fibers that remain show higher synaptic field […]

   Although it is well established that the perirhinal cortex (PRC) makes an important contribution to recognition memory, the specific nature of this contribution remains uncertain. The finding that PRC activity is reduced for old compared to new items is typically attributed to the recovery of a long-term memory signal. However, because old items are […]

The present investigation tested the novel prediction that encoding-retrieval similarity can be observed and related to memory at the level of individual items. Multivariate representational similarity analysis was applied to functional magnetic resonance imaging (fMRI) data collected during encoding and retrieval of emotional and neutral scenes. Memory success tracked fluctuations in encoding-retrieval similarity across frontal and posterior cortices. Importantly, medicine […]

Although ventral parietal cortex (VPC) activations can be found in a variety of cognitive domains, recipe these activations have been typically attributed to cognitive operations specific to each domain. In this article, we propose a hypothesis that can account for VPC activations across all the cognitive domains reviewed. We first review VPC activations in the domains of perceptual and […]

Studies of cognitive and neural aging have recently provided evidence of a shift from an early- to late-onset cognitive control strategy, troche linked with temporally extended activity in the prefrontal cortex (PFC). It has been uncertain, however, whether this age-related shift is unique to PFC and executive control tasks, or whether the functional location might […]

Dew and Cabeza (2011) review behavioral and neuroimaging evidence showing that, check under certain circumstances, viagra sale there may be an important and influential relationship between conscious and nonconscious forms of memory. Here, we offer a model predicting that the brain regions associated with explicit or implicit memory are not differentiated based on consciousness, but […]

  Emotion processing has been shown to vary with age: relative to young adults (YAs), older adults (OAs) exhibit increased frontal activations to emotional materials as well as cognitive biases toward positive versus negative stimuli. This latter effect is hypothesized to depend on OAs’ capacity for controlled elaboration. To test this hypothesis, YAs and OAs […]

Whereas ventral mPFC (medial prefrontal cortex) has been associated with inferences about one’s own self, dorsal mPFC has been associated with inferences about others. We investigated this distinction using a novel camera technology that automatically takes hundreds of photographs when worn. We fMRI-scanned young participants while viewing movie clips depicting events from their own life […]